In 2007, the renowned pain researcher Dr. Sota Omoigui, published an article in the medical journal Medical Hypothesis called, "The Biochemical Origin of Pain: The Origin of All Pain is Inflammation and the Inflammatory Response." In it, he demonstrated the relationship between pain, inflammation, and fibrosis (Scar Tissue). Most people tend to think of Inflammation as a "local" phenomenon. You know; sprain an ankle, and it swells and sometimes a great deal. But it is critical to remember that the terms "swelling" and "inflammation" are in no ways synonymous. When the soft tissues are seriously injured as in ankle, shoulder, and knee sprains and especially Whiplash Injuries they die. These dead cells then rupture their contents into the surrounding extra-cellular fluid. In response to this, the Immune System makes a group of chemicals that we collectively refer to as "Inflammation", which in small amounts, are normal and good. Their local presence is indicated by five well known signs and symptoms. The classical names for the various signs of Local Inflammation come from Latin and include:

  • Dolar (Pain)

  • Calor (Heat)

  • Rubor (Redness)

  • Tumor (Swelling) The chemicals we collectively call "Inflammation" are not synonymous with swelling, but they attract swelling.

  • Functio Laesa (Loss of Function)

Although these chemicals can remain in a local area such as injuring the big toe and it becomes red and inflamed, they can invade the blood stream and have a systemic (whole body) effect as well. But inflammation does not end there. These immune system chemicals that we refer to collectively as "inflammation" (prostaglandins, leukotrienes, thromboxanes, cytokines, chemokines, certain enzymes, kinnins, histamines, eicosanoids, substance P, and dozens of others) are being touted by the medical community as the primary cause of a whole host of physical ailments, when there are too many of them in the body.

Other associated problems inflammation is known to cause includes;

  • Disc Injuries, Slipped Disc, Disc Herniation, and Disc Rupture

  • Heart Disease and virtually all forms of Cardiovascular Problems

  • Skin conditions including Eczema and Psoriasis

  • Arthritis & Fibromyalgia

  • Asthma

  • ADD, ADHD, Depression, and various forms of Dementia

  • Neurological Conditions

  • Female Issues

  • Cancer

  • Inflammatory Bowel Disease / Leaky Gut Syndrome

  • Diabetes, Insulin Resistance, Hypoglycemia, and other Blood Sugar Regulation Problems

  • Obesity

Simply put; inflammation causes pain, ill health, and eventually can even cause death. But this list is not the thrust of this section. What I want you to understand is the intimate way that inflammation is related to Scar Tissue, Adhesion, and Fibrosis.

Born in 1904, Dr. Sir James Cyriax, a Cambridge-educated M.D. widely known as the "The Einstein of Physical Medicine" wrote his Magnum Opus, Orthopaedic Medicine, Diagnosis of Soft Tissue Lesions, in 1982 shortly before he passed away.

Sir James Cyriax is still considered one of the brilliant pioneers of soft tissue research. One of Dr. Cyriax' groundbreaking discoveries was that Scar Tissue / Fibrosis can and will generate an Inflammatory Response long after the Fourth Stage of Healing (Maturation & Remodeling) is over. Pay attention to what Cyriax wrote over three decades ago.

Fibrous tissue appears capable of maintaining an inflammation, originally traumatic, as the result of a habit continuing long after the cause has ceased to operate...... It seems that the inflammatory reaction at the injured fibers continues, not merely during the period of healing, but for an indefinite period of time afterwards, maintained by the normal stresses to which such tissues are subject.”

Why is it that Sir James Cyriax refers to as "normal mechanical stresses" cause an "indefinite period" of inflammation? Because Scar Tissue and Fibrosis are so dramatically different from normal tissue. One of the most obvious ways that this can be seen is by looking at any good Pathology Textbook. Scar Tissue and Fibrosis is far weaker and much less elastic than normal Connective Tissue.

What does this mean? Only that it is easily re-injured because it is weaker tissue, less elastic, it is a pain generator and it is easily re-injured and this starts the whole vicious cycle over again. Injury - Inflammation - Pain - Fibrosis & Scar Tissue Formation - Re-injury - leading to chronic pain patterns and it is repeated indefinitely for life. Just remember that the end result of this cycle is degeneration soft tissues such as muscles, tendons, ligaments, discs and even can adversely affect bones!

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